Jim Perfield

Jim Perfield

Company: Eli Lilly & Company

Job title: Executive Director Discovery Biology, Diabetes, Obesity & Complications

Seminars:

Panel Discussion: Liver Organoids, Precision-Cut Liver Slices & Animal Models: Interrogating Diverse Preclinical Models to Understand Pathophysiology & Screen Targets 12:00 pm

Which are the best preclinical models? Recapitulating complex architecture and metabolic function in liver tissue to test therapeutic efficacy Investigating emerging platforms and technologies for disease modeling and regenerative therapy From research to therapeutics application: bringing the translational gapRead more

day: Day 2 Stream 1 AM

Results from the LITMUS Preclinical Retrospective Study: A Novel Unbiased Approach to Rank Murine NASH Models Based on Proximity to Human Disease 11:30 am

Review how a wide-ranging retrospective review of 42 commonly used murine models was conducted Learn how a novel algorithm was developed to evaluate preclinical models to human NASH in 3 categories: phenotype, histology, and liver transcriptome Discover how separate rankings are provided for models based on relevance to NAFLD development and NASH fibrosisRead more

day: Day 2 Stream 1 AM

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