Unravelling a Liver-Adipose Feedback Loop Involving Hepatic Activin E to Elucidate Novel Therapeutic Opportunities to Regulate Body Fat Distribution

Time: 1:40 pm
day: Day 2 Seminar A Post-Lunch Tracks


  • Activin E mediates liver-adipose inter-organ communication, suppressing adipose lipolysis to regulate hepatic triglyceride
  • Identifying the role of the ALK7/Activin E signaling axis in the regulation of body fat distribution
  • Detailing how disruption of the Activin E/ALK7 inter-organ communication loop in mice leads to insulin resistance and hepatic steatosis