The “Free Choice” Diet-Induced Obese Hamster for Evaluating Drugs Targeting NASH & Fibrosis: A Promising Alternative to Mouse & Rat Models
Time: 11:30 am
day: Day 2 Stream 1 AM
Details:
- Emphasizing the limitations of diet-induced mouse and rat models for evaluation of drugs targeting NASH/liver fibrosis
- Describing the free choice diet-induced obese hamster as a preclinical model for NASH, liver fibrosis and associated heart failure with preserved ejection fraction
- Presenting the effects of clinical benchmarks demonstrating the relevance of the hamster model for drug efficacy studies
