Results from the LITMUS Preclinical Retrospective Study: A Novel Unbiased Approach to Rank Murine NASH Models Based on Proximity to Human Disease

Time: 11:30 am
day: Day 2 Stream 1 AM


  • Review how a wide-ranging retrospective review of 42 commonly used murine models was conducted
  • Learn how a novel algorithm was developed to evaluate preclinical models to human NASH in 3 categories: phenotype, histology, and liver transcriptome
  • Discover how separate rankings are provided for models based on relevance to NAFLD development and NASH fibrosis