Cholestatic & Metabolic Liver Disease: Uncovering A Mechanistic Understanding of FXR Agonist Induced Pruritus & its Therapeutic Potential

Time: 4:00 pm
day: Day Two


  • Defining mechanistic understanding of FXR agonist induced pruritus and cholestatic pruritus
  • Uncovering a key pruritogenic cytokine, IL31, as a candidate target of FXR agonism
  • Investigating translation to the clinic: correlating IL31 with degree and severity of itch